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MainSheet Ventures

MainSheet Ventures

Amherst, New Yorkmainsheetventures.com

Overview

MainSheet Ventures is a venture capital investment firm founded in 2024. Based in Amherst, New York, the firm focuses on investing in early-stage companies operating in the healthcare, med tech/devices, robotics, artificial intelligence, software, and consumer brands sectors.

Portfolio Companies

8

Investments

MainSheet Ventures investments
CompanyDateStageLead
Phantom NeuroApr 2025Series ACo-investor
Runway HealthJun 2022Pre SeedCo-investor
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Sector & Stage Mix

Industry, funding stage, and valuation band breakdowns.

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SeedSeries ASeries BGrowth

Portfolio analytics

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Investment Activity

Yearly cadence, pace, and funding raised over time.

Premium
2021
2022
2023
2024
2025
2026

Portfolio analytics

Caplight clients see yearly investment pace and funding raised over time.

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FAQ

Where is MainSheet Ventures based?

MainSheet Ventures is headquartered in Amherst, New York, United States.

When was MainSheet Ventures founded?

Founding year information for MainSheet Ventures is not publicly available.

How many portfolio companies does MainSheet Ventures have?

MainSheet Ventures has 8 portfolio companies in Caplight's dataset.

What are some companies in MainSheet Ventures's portfolio?

Portfolio companies visible on Caplight include Phantom Neuro, Runway Health.

What was MainSheet Ventures's most recent investment shown here?

MainSheet Ventures's most recent investment in this portfolio sample was in Phantom Neuro in 2025.

What sectors does MainSheet Ventures focus on?

MainSheet Ventures focuses on Healthcare & Life Sciences, Healthcare & Life Sciences, Healthcare & Life Sciences, Healthcare & Life Sciences, Consumer & Commerce, Frontier & Industrial Tech, Healthcare & Life Sciences, Healthcare & Life Sciences, Enterprise Software, Enterprise Software, Media, Entertainment & Gaming, AI, Data & Cloud Infrastructure, Frontier & Industrial Tech, Consumer & Commerce, Frontier & Industrial Tech, Consumer & Commerce.

What company stages does MainSheet Ventures focus on?

MainSheet Ventures typically invests at the Early stage.

Firmographic Details

HeadquartersAmherst, New York
Year FoundedN/A

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