Lightstone Ventures
Overview
Lightstone Ventures is a global venture capital firm investing in biotech and medtech companies pioneering big ideas poised to transform patient outcomes . The firm empowers visionary entrepreneurs with the resources and operational guidance necessary to bring their innovative therapeutics and technologies to the patients who need them most . Lightstone seeks to identify and support innovative life science companies that have the potential to make a significant impact on human health . With a strong focus on working closely with their portfolio companies, Lightstone provides both financial support and strategic guidance to help these companies achieve their full potential .
Investments
| Company | Date | Stage | Lead |
|---|---|---|---|
| Tizona Therapeutics | Mar 2016 | Series B | Co-investor |
| Atsena Therapeutics | Apr 2025 | Series C | Co-investor |
| Shoulder Innovations, Inc. | Mar 2023 | Series D | Co-investor |
| Crystalys Therapeutics | Jul 2026 | Series B | Co-investor |
| Volta Medical | Jan 2023 | Series B | Co-investor |
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Key People
Mark Deem
Operating Partner
Caroline G.
Partner
Hanson Gifford
Partner
Ralph Christoffersen
Special Partner
Brendan Kelly
Principal
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Sector & Stage Mix
Industry, funding stage, and valuation band breakdowns.
FAQ
Where is Lightstone Ventures based?
Lightstone Ventures is headquartered in Menlo Park, California, United States.
When was Lightstone Ventures founded?
Lightstone Ventures was founded in 2012.
How many portfolio companies does Lightstone Ventures have?
Lightstone Ventures has 29 portfolio companies in Caplight's dataset.
What are some companies in Lightstone Ventures's portfolio?
Portfolio companies visible on Caplight include Tizona Therapeutics, Atsena Therapeutics, Shoulder Innovations, Inc., Crystalys Therapeutics, Volta Medical.
What was Lightstone Ventures's most recent investment shown here?
Lightstone Ventures's most recent investment in this portfolio sample was in Crystalys Therapeutics in 2026.
What sectors does Lightstone Ventures focus on?
Lightstone Ventures focuses on Healthcare & Life Sciences, Healthcare & Life Sciences, Healthcare & Life Sciences, Healthcare & Life Sciences, Healthcare & Life Sciences, Healthcare & Life Sciences, Healthcare & Life Sciences, Healthcare & Life Sciences, Healthcare & Life Sciences, Healthcare & Life Sciences, Healthcare & Life Sciences, Healthcare & Life Sciences, Healthcare & Life Sciences, Healthcare & Life Sciences, Healthcare & Life Sciences, Healthcare & Life Sciences, Healthcare & Life Sciences, Healthcare & Life Sciences, Healthcare & Life Sciences, Healthcare & Life Sciences, Healthcare & Life Sciences, Healthcare & Life Sciences, Healthcare & Life Sciences, Healthcare & Life Sciences, Healthcare & Life Sciences, Healthcare & Life Sciences, Healthcare & Life Sciences, Healthcare & Life Sciences, Healthcare & Life Sciences, Consumer & Commerce, Enterprise Software, AI, Data & Cloud Infrastructure, Frontier & Industrial Tech.
What company stages does Lightstone Ventures focus on?
Lightstone Ventures typically invests at the MultiStage stage.
What is Lightstone Ventures's AUM?
Lightstone Ventures's assets under management are estimated between $500.0M and $1.0B.