Define Ventures
Overview
Define Ventures is a Silicon Valley-based venture capital firm that focuses exclusively on investing in early-stage digital health startups at the incubation, seed, Series A, and Series B stages. The firm's strategy centers on partnering with companies that serve multiple ecosystem partners, including consumers, payers, providers, employers, and life-sciences companies, combining Silicon Valley principles with deep healthcare operating experience.
Portfolio Companies
38
Website
definevc.comInvestments
| Company | Date | Stage | Lead |
|---|---|---|---|
| Unite Us | Mar 2021 | Series C | Co-investor |
| Hims & Hers Health, Inc. | Jan 2021 | IPO | Co-investor |
| UpStream | Dec 2022 | Series B | Co-investor |
| Cohere Health | May 2025 | Series C | Co-investor |
| Tia | Sep 2021 | Series B | Co-investor |
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Key People
Lynne Chou O'Keefe
Founder and Managing Partner
Sector & Stage Mix
Industry, funding stage, and valuation band breakdowns.
FAQ
Where is Define Ventures based?
Define Ventures is headquartered in San Francisco, California, United States.
When was Define Ventures founded?
Founding year information for Define Ventures is not publicly available.
How many portfolio companies does Define Ventures have?
Define Ventures has 38 portfolio companies in Caplight's dataset.
What are some companies in Define Ventures's portfolio?
Portfolio companies visible on Caplight include Unite Us, Hims & Hers Health, Inc., UpStream, Cohere Health, Tia.
What was Define Ventures's most recent investment shown here?
Define Ventures's most recent investment in this portfolio sample was in Cohere Health in 2025.
What sectors does Define Ventures focus on?
Define Ventures focuses on Healthcare & Life Sciences, Healthcare & Life Sciences, Healthcare & Life Sciences, Healthcare & Life Sciences, Healthcare & Life Sciences, Healthcare & Life Sciences, Healthcare & Life Sciences, Healthcare & Life Sciences, Healthcare & Life Sciences, Healthcare & Life Sciences, Healthcare & Life Sciences, Healthcare & Life Sciences, Healthcare & Life Sciences, Healthcare & Life Sciences, Healthcare & Life Sciences, Healthcare & Life Sciences, Healthcare & Life Sciences, Healthcare & Life Sciences, Healthcare & Life Sciences, Healthcare & Life Sciences, FinTech, AI, Data & Cloud Infrastructure, Healthcare & Life Sciences, Healthcare & Life Sciences, Healthcare & Life Sciences, Healthcare & Life Sciences, Healthcare & Life Sciences, AI, Data & Cloud Infrastructure, Healthcare & Life Sciences, Healthcare & Life Sciences, Energy & Sustainability, Healthcare & Life Sciences, Enterprise Software, Frontier & Industrial Tech, Healthcare & Life Sciences, Crypto & Web3, Healthcare & Life Sciences, Healthcare & Life Sciences, Enterprise Software, Healthcare & Life Sciences, AI, Data & Cloud Infrastructure, Enterprise Software, Frontier & Industrial Tech, Media, Entertainment & Gaming, Enterprise Software, Enterprise Software, Enterprise Software, AI, Data & Cloud Infrastructure, FinTech, Enterprise Software, Enterprise Software, Enterprise Software, Enterprise Software, AI, Data & Cloud Infrastructure, Enterprise Software, Enterprise Software, Consumer & Commerce, AI, Data & Cloud Infrastructure, Enterprise Software, Enterprise Software, Enterprise Software, Enterprise Software, AI, Data & Cloud Infrastructure, Enterprise Software, Enterprise Software, Enterprise Software, Enterprise Software, Frontier & Industrial Tech, Enterprise Software, Enterprise Software, Enterprise Software.
What company stages does Define Ventures focus on?
Define Ventures typically invests at the Early stage.
What is Define Ventures's AUM?
Define Ventures's assets under management are estimated between $800.0M and $800.0M.