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Isto Biologics

Isto Biologics

Private
Hopkinton, MassachusettsHealthcare & Life Scienceshttps://istobiologics.com/

Last Round

Buyout/LBO

Sep 17, 2025

Est. Valuation

$1B

Total Funding Raised

$37.8M

Momentum

Top 25%

of companies Caplight tracks

Company Overview

Isto Biologics is a biotechnology company that manufactures orthobiologic medical devices, including autologous concentration systems, allografts, and biosynthetic bone grafts, for use in spine, orthopedics, and sports medicine.

Sector

Healthcare & Life Sciences

Verticals

Biotechnology, Medical Devices, Advanced Materials, Precision Medicine

Business Model

B2B

Customer Profile

Hardware Sales, Services & Consulting

AI Layer

Non-AI

Keywords

orthobiologicsbone graftautologous therapyplatelet-rich plasmaPRPregenerative medicinesurgical biologicsallograftbone graft substitutespine surgerymedical devicemedtechconcentrated bone marrow aspiratecBMAspinal fusionsports medicineautologous concentration system

Historical Pricing

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Caplight Momentum Score

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Isto Biologics Comparables

Compare Isto Biologics with similar companies based on industry and business-model similarity.

Isto Biologics comparables — related companies by embedding similarity
CompanySimilarityMarket Cap
Royal Biologics
79%
Xtant Medical Holdings
79%
VIVEX Biologics
78%

Isto Biologics Funding Rounds

Historical fundraising activity

Data table
RoundDateAmount RaisedValuationInvestorsSources
Buyout/LBOSep 17, 2025
M&AOct 25, 2023
Buyout/LBOJun 3, 2016
DebtMar 18, 2014
Growth EquityOct 25, 2007
Series E
Aug 1, 2007

Isto Biologics Investors

Notable investors and investment history

Isto Biologics investors
InvestorRounds
DW Healthcare PartnersGrowth Equity
EQT Life SciencesSeries E, Series D
Mid-America Transplant ServicesSeries E, Series D
Thompson Street Capital PartnersBuyout/LBO, M&A
Keensight CapitalBuyout/LBO
Alafi CapitalSeries E, Series D
Ascension VenturesSeries E

Market signals

Structured signals derived from secondary market and firmographic data.

  • Jul 20, 2026

    Open roles increased to 43, 331% of headcount.

  • Sep 17, 2025

    $1.0B round led by Keensight Capital

Recent news

Latest coverage and updates

  • acquiresAug 4, 2026

    Isto Biologics acquired NovaBone Products, LLC for $60.7M on Aug 4th '26.

Isto Biologics Filings

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Isto Biologics filings preview — column headings only; records require access
TypeDateAmount OfferedAmount SoldFilingPagesDownload

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Firmographic Details

HeadquartersHopkinton, Massachusetts
Employee Range13
Year Founded1997
Last FundingSep 17, 2025

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