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HotSpot Therapeutics

HotSpot Therapeutics

Private
Boston, MassachusettsHealthcare & Life Scienceshttps://www.hotspotthera.com/

Last Round

Series C

Nov 29, 2021

Total Funding Raised

$210M

Company Overview

HotSpot Therapeutics is a biotechnology company that pioneers allosteric drug discovery by identifying and targeting natural regulatory hotspots on proteins to develop differentiated small molecule medicines for autoimmune diseases and cancer.

Sector

Healthcare & Life Sciences

Verticals

Biotechnology, Drug Discovery

Business Model

B2B

Customer Profile

Revenue Share

AI Layer

Application

Keywords

small moleculedrug discoveryallosteric inhibitorsbiotechprecision medicineoncologyautoimmune diseaseundruggable targetsAI drug discoverypreclinical researchcomputational biologypharma partneringin silico drug designtechbio

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Caplight Momentum Score

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HotSpot Therapeutics Comparables

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HotSpot Therapeutics comparables — related companies by embedding similarity
CompanySimilarityMarket Cap
Exo Therapeutics
85%
Allorion Therapeutics
84%
Nimbus Therapeutics
83%

HotSpot Therapeutics Funding Rounds

Historical fundraising activity

Data table
RoundDateAmount RaisedValuationInvestorsSources
Series CNov 29, 2021
Series BMay 21, 2020
Series AJul 17, 2018

Key People

Founding team and executive leadership

Jonathan Montagu

President Chief Executive Officer

Executive Team

Eva Jack

Chief Operating Officer

Executive Team

HotSpot Therapeutics Investors

Notable investors and investment history

HotSpot Therapeutics investors
InvestorRounds
Brace Pharma CapitalSeries B
EQT Life SciencesSeries C
B Capital GroupSeries C
Pivotal bioVenture PartnersSeries C
Tekla Capital ManagementSeries B, Series C
Nan Fung GroupSeries C
Solasta VenturesSeries B

Market signals

Structured signals derived from secondary market and firmographic data.

  • Mar 4, 2026

    Presented preclinical data at the 15th European Lupus Meeting.

  • Mar 4, 2026

    Launched interferon regulatory factor 5 (IRF5) program with preclinical data.

Recent news

Latest coverage and updates

  • is_developingAug 18, 2026

    HotSpot Therapeutics, Inc. is developing HST-2011.

  • is_developingAug 18, 2026

    HotSpot Therapeutics, Inc. is developing novel allosteric therapies for the treatment of autoimmune diseases.

  • hiresAug 18, 2026

    HotSpot Therapeutics, Inc. hired Niti Goel as Chief Medical Officer on Aug 18th '26.

HotSpot Therapeutics Filings

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HotSpot Therapeutics filings preview — column headings only; records require access
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Frequently Asked Questions

Common questions about HotSpot Therapeutics's valuation, stock price, and market status.

Is HotSpot Therapeutics a public or private company?

HotSpot Therapeutics is a private company.

What is the current stock price of HotSpot Therapeutics?

HotSpot Therapeutics is a private company with no public stock price. No recent secondary market data is available.

How much is HotSpot Therapeutics worth (valuation)?

Valuation information for HotSpot Therapeutics is not publicly available.

Can I buy HotSpot Therapeutics stock?

HotSpot Therapeutics shares may be available on secondary markets subject to transfer restrictions. Caplight facilitates secondary market transactions for accredited investors. Visit https://www.caplight.com to learn more.

When was HotSpot Therapeutics's last funding round?

HotSpot Therapeutics's most recent funding round was Series C on November 29, 2021.

Who are the main investors in HotSpot Therapeutics?

Key investors in HotSpot Therapeutics include Pivotal bioVenture Partners, Nan Fung Group, Sofinnova Partners, Pivotal bioVenture Partners, Atlas Venture.

Will HotSpot Therapeutics IPO soon?

No public IPO plans have been announced for HotSpot Therapeutics.

How can I track HotSpot Therapeutics secondary market activity?

Caplight tracks bids, offers, and trades for private companies. Visit https://www.caplight.com to monitor HotSpot Therapeutics's secondary market activity and sign up for updates.

Firmographic Details

HeadquartersBoston, Massachusetts
Employee Range58
Year Founded2017
Last FundingNov 29, 2021

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